منابع مشابه
Effect of Vitamin D treatment on Interleukin-2 and Interleukin-4 Genes expression in Multiple Sclerosis
Introduction: Multiple sclerosis is a chronic inflammatory disease of central nervous system. The etiology of MS is slightly known, but genetic and environmental factors are reported. Vitamin D regulates gene expression and affects target cell functions. The aim of this study was to investigate the expression variation of IL-2 and IL-4 genes under vitamin D supplementation in patients with mult...
متن کاملThe interleukin-2 receptor.
The human body defends itself against foreign invaders such as bacteria and viruses by a defense system that involves antibodies and thymus-derived lymphocytes (T cells). A major advance over the past decade has been the demonstration that the diverse cells within the immunological network communicate with each other not only by cell/cell contact but also by an array of hormone-like proteins te...
متن کاملInterleukin 2 in Neuroblastoma
Neuroblastoma is one of the most common solid tumors in childhood, with some unusual neoplastic behavior depending on the age of the affected children. Patients older than 1 year who have metastatic disease have a very poor prognosis. However, in children younger than 1 year who have disseminated disease, regression of neuroblastoma often occurs after only minimal therapy, or even spontaneously...
متن کاملInterleukin 2 receptor-targeted cytotoxicity. Interleukin 2 receptor- mediated action of a diphtheria toxin-related interleukin 2 fusion protein
The IL-2 toxin-mediated inhibition of protein synthesis in high affinity IL-2-R-positive murine and human T cell lines has been examined. Both excess free IL-2 and mAb to the Tac epitope of the p55 subunit of IL-2-R are shown to block the action of IL-2 toxin; whereas, agents that interact with other receptors or antigens on the T cell surface have no effect. We show that IL-2 toxin, like dipht...
متن کاملeffect of vitamin d treatment on interleukin-2 and interleukin-4 genes expression in multiple sclerosis
introduction: multiple sclerosis is a chronic inflammatory disease of central nervous system. the etiology of ms is slightly known, but genetic and environmental factors are reported. vitamin d regulates gene expression and affects target cell functions. the aim of this study was to investigate the expression variation of il-2 and il-4 genes under vitamin d supplementation in patients with mult...
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ژورنال
عنوان ژورنال: BMJ
سال: 1990
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.300.6726.746-a